Scavenging in the junkyard, Doctor Daisuke discovers the head of a cyborg girl. She has lost her memory, so he names her Alita. As he tries to find parts to rebuild her, he discovers that she may not be the angel he had sought to create. His dreams of tranquility are replaced by his recognition of the incredible martial skills she instinctively possesses, and they are drawn into the consequences that having such power can bring.